A drug that reduces the action of another drug, generally an agonist Antagonists can act by a number of different mechanisms: Pharmacological antagonism: Interaction at the same receptor macromolecule as the agonist Chemical antagonism: Combination with the substance...
Description The graph is a log dose-response curve with log drug dose on the x-axisHowever, the y-axis shows % response of maximal response and is drawn to show both a poitive and negative responseThe curve of an antagonist is sigmoid in shape and is a reflection of...
Description The graph is a log dose-response curve with log drug dose on the x-axis and % of maximal effect on the y-axisAn antagonist displays no effect regardless of the concentration and thus follows a horizontal linear path at 0%...
Description The graph is a log dose-response curve with log drug dose on the x-axis and % of maximal effect on the y-axisThe curve sigmoid in shapeThe height of the curve is the maximal effect which for a partial agonist is lower than 100%The curve always passes...
Description The graph is a log dose-response curve with log drug dose on the x-axis and % of maximal effect on the y-axisThe curve sigmoid in shapeThe height of the curve is the maximal effect which for a full agonist is 100%The curve always passes through the ED50For...
