Total calcium levels are generally dependent on the level of plasma albumin With reduced serum albumin proportionally less calcium is bound This results in a lower measured total plasma...
Total calcium levels are generally dependent on the level of plasma albumin With reduced serum albumin proportionally less calcium is bound This results in a lower measured total plasma calcium A corrective formula (Payne’s formula) is commonly applied to...
Ca2+ ions competes for binding sites on albumin with H+ ions As pH changes the proportion of calcium bound to albumin and freely ionised in the plasma varies For every 0.1 unit reduction in plasma pH, the albumin bound calcium decreases by 0.07 mmol/L and ionised...
