Bone formation and metabolism: Contributes to strength and structure Role as a strong cation in acid-base balance Coagulation of blood (cofactor in coagulation pathway) Cellular functions: Excitation–contraction coupling in cardiac, skeletal and smooth muscle Cardiac...
The protein calmodulin activates many enzymes in the presence of calcium: Calcium-calmodulin complexes bind to enzymes acting as a co-factor Known as a ‘calcium-binding regulatory protein’ Enzymes activated by calmodulin include: Glycogen synthase Adenyl...
Ionized calcium is essential for many stages of both coagulation and platelet plug formation Multiple roles in coagulation pathway (Calcium is known as Factor IV): Required for the activation of factors VII, IX and X Acts as a co-factor in the conversion of...