How does SJS / TEN present?

Usually presents with prodrome for 2–3 days of fever, flu-like illness and malaise Features can be described as those affecting: the skin, mucous membranes (involvement is characteristic of SJS / TEN) and extra-cutaneous sites Skin Initial Phase:Erythematous, dusky...

What is the differential diagnosis for SJS / TEN?

Erythema multiforme major Acute generalized erythematous pustulosis Intermediate burns Generalized Fixed Bullous Drug Eruption Staphylococcal Scalded Skin Syndrome Edematous erythroderma Bullous pemphigoid Paraneoplastic pemphigus Linear IgA Bullous Dermatosis Lupus...

How do you work up the patient with suspected SJS / TEN?

Usually presents with prodrome for 2–3 days of fever, flu-like illness and malaise Features can be described as those affecting: the skin, mucous membranes (involvement is characteristic of SJS / TEN) and extra-cutaneous sites Skin Initial Phase:Erythematous, dusky...

Which score can be used to assess prognosis in SJS / TEN?

The SCORTEN is a validated scoring system to predict mortality This should be scored within 24 hours of admission. Age >40 Malignancy Initial area greater >10% Heart rate >120 Serum urea >10 Serum glucose >14 Serum bicarbonate <20 Score 0-1 2 3 4 5...

What is the management of SJS / TEN?

Key PrinciplesEarly recognition and withdrawal of offending agentsMultidisciplinary supportive care in burns centreStrict infection control as per BAD guidelines Initial Resuscitation & Supportive Care ABC approach treating abnormalities as found:May require...