• Plateau pressure represents the pressure required to expand the lungs to a set volume in the absence of flow:
    • Reflects the pressure to overcome pulmonary compliance
  • This is different from the peak airway pressure, which describes the pressure to expand the lungs during flow:
    • Consists of the plateau pressure and the airway pressure
    • Influenced by factors other than lung compliance – inspiratory flow rate, ETT size, secretions etc
  • The plateau pressure is essential for deriving the “driving pressure.”
    • The difference between PEEP and plateau pressure represents the driving pressure
    • High driving pressures more predictive of injury than either of the component variables
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  • The plateau pressure can be measured during a period of no-flow:
    • Inspiratory pause manoeuvre can be used on most ventilators
    • Pressure should be measured 0.5 seconds into the pause manoeuvre