• Functional unit of the thyroid is the follicle:
    • Outer sphere of cuboidal epithelial cells (thyrocytes) and thin basement membrane:
      • Site of thyroglobulin production
    • Filled with a protein rich core called colloid:
      • Made up of thyroglobulin a large glycoprotein
      • Serves as the main storage of thyroid hormones
  • C-cells are dispersed between follicles to produce calcitonin