- Significant risk of MI and death
- Compensatory mechanisms for fixed output state disrupted by anaesthesia
- Anaesthesia induces a reduction in SVR
- Fixed obstruction in AS impedes compensatory increase in cardiac output
- Resulting hypotension can lead to reduced myocardial perfusion and ischaemia
- Induces a downward spiral of reduced contractility, further hypotension and ischaemia
- Risk of arrhythmias
- General anaesthesia can reduce sinus node automaticity
- Can lead to nodal rhythms or other arrhythmias (AF or atrial tachycardias)
- Risk of infective endocarditis
