What are the laboratory features of TTP?

  • Features of MAHA:
    • Anaemia on FBC
    • Blood film: low platelets, schistocytes, polychromasia
    • Increased reticulocytes, bilirubin and LDH
    • Negative DAT Coomb’s test
  • Marked thrombocytopenia
  • Decreased ADAMTS13 activity
    • Anti-ADAMTS13 IgG may be identified