- The Texas children’s study (Allen et al) suggested:
- >500 has 100% sensitivity
- >10,000 has 90% sensitivity and 96% specificity
- Believe that the very high ferritin levels are not just the product of the inflammation but instead may have a pathogenic role
- May be involved in some sort of a loop mechanism where ferritin’s inflammatory proprieties are exacerbated, leading to an extreme expression of additional inflammatory mediators that are characteristic in the cytokine storm.