- Dosing during RRT can be challenging given the numerous factors needed to be accounted for:
- Should not simply be dosed for reduced GFR
- Nomograms developed for use in stable patients on IHD can result in significant under-dosing
- Drug levels should be measured to aid dosing whenever possible
- In the absence of drug levels:
- ‘Bedside’ dosing guidelines should be used (e.g. ‘Renal Drug Handbook’)
- Expert pharmacist help should be sought when possible
