How common is aortic stenosis? What is the natural course and prognosis of aortic stenosis?

(Adapted from ESC/EHA Guidelines)

• Classically associate with a prolonged asymptomatic period followed by rapid progression of symptoms
  • Asymptomatic disease:
    • Risk of sudden death of 1%
  • Symptomatic disease:
    • Poor prognosis without valve replacement
    • Average survival 2-5 years
    • 50% incidence of sudden death and a monthly mortality of 2%
• There is no definitive evidence that medical treatment alone can slow disease progression