Biocompatibility Flux Adsorption Thickness Surface area Material The rate of blood flow from the patient towards the filterBlood flow rates are typically slower than in intermittent dialysis, ranging from 150-200mL/min The rate at which ultrafiltrate is produced by...
The filtration fraction is a measure of haemoconcentration in the filter It is defined by the ratio between volume removed by convection per volume of plasma flow If the ratio is too high, the filter tends to clot – more concentrated blood is ‘stickier’ and more...
Normal filter blood flows range between 50-200mL/min Choosing the appropriate flow is a trade-off between the advantages and disadvantages of high and low flows: High Blood Flows Low Blood Flows Advantages A lower filtration fraction required thus reducing the risk of...
In ultrafiltration, the effluent rate is determined by the flow of plasma into the membrane and the fraction of this which is filtered out as effluent (known as the filtration fraction) To maintain a constant effluent rate: At low blood flows a large filtration...
Clearance describes the volume of blood that is cleared of a substance per unit of time The determinant of clearance in CRRT depends upon the mechanisms that are being utilised In continuous haemofiltration: A volume of ultrafiltrate is produced following the passage...
