Features Liver function is initially immature, with decreased hepatic enzyme function Renal blood flow and glomerular filtration rate are low in the neonate and young infant due to increased vascular resistance Reach adult levels between 1 and 2 years age Loop of...
Features Innate immune system is muted at birth and matures with increasing age The adaptive immune system is immature, providing increased protection over time with accumulation of immunological memoryNeonates and young infants receive IgG antibody transfer from the...
Features Foetal haemoglobin (HbF) forms, 70-90% of the haemoglobin molecules at birthDrops to around 5% HbF by 3 months with HbA predominatingFoetal haemoglobin contains less 2,3-DPG and combines more readily with oxygen Haemoglobin levels change rapidly with...
Features Liver function is initially immature, with decreased hepatic enzyme function Liver and spleen ride comparatively low within the abdomen and have minimal protection from ribsIntestines, especially the sigmoid and right colon, are not fully attached in the...