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What are the indications for surgical and radiological interventions in severe acute pancreatitis?

Relieving biliary obstruction (e.g. ERCP) Removing infected intra- and extra-pancreatic necrosis (Necrosectomy) Pancreatic duct disruption Management of symptomatic masses due to pseudocysts or sterile necrosis: Gastric outlet or intestinal obstruction Persistent...

What nutrition therapy should patients with severe acute pancreatitis receive?

Early EN is now standard of care in patients with acute pancreatitis Recent research suggests improved outcomes compared with previous strategies of pancreatic rest with TPN Guidance recommends commencing within 72 hours if intolerant of oral intake Enteral nutrition...

Which patients should receive antibiotics in severe acute pancreatitis?

Antibiotics should be used in any case of pancreatitis complicated by infected pancreatic necrosis but should not be given routinely for fever, especially early in the presentation: Carbapenem usually the best class due to penetration in to pancreatic tissue Fungal...

Which patients with pancreatitis should be referred to the regional centre?

All patients with necrotizing pancreatitis with the following features should be referred to a regional HPB centre for discussion: Greater than 30% necrosis of the pancreas or ANCs on early CT (within seven days of admission) Persisting organ dysfunction for greater...

Which patients with pancreatitis should be admitted to critical care?

UK guidelines state that all patients with acute severe pancreatitis should be managed on the high dependency unit (HDU): Can be difficult in practice – ensure all referred to the critical care outreach team for regular review and escalation of care if...
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