Normal rate of production is 0.3-0.4ml/min or 20ml/hour or 500ml/day Results in effective replacement of CSF volume 3x daily Production is largely independent of ICP: Raised ICP is compensated by increased absorption of CSF reducing total volume Decreased when CPP...
Normal rate of production is 0.3-0.4ml/min or 20ml/hour or 500ml/day Results in effective replacement of CSF volume 3x daily Production is largely independent of ICP: Raised ICP is compensated by increased absorption of CSF reducing total volume Decreased when CPP...
Produced by the four choroid plexuses: Located in the two lateral, third, and fourth ventricles Highly vascular invaginations of pia mater Covered by specialised ciliated ependymal cells Produced by a combination of: Filtration of plasma through the fenestrated...
CSF pressure is gravitational and varies with position In the lateral position normal pressure is 5-20 cm of H2O In the sitting position: Pressure in the lumbar region rises to 20-50 cmH20 Pressure in the cervical region may be...
Mechanical Protection Maintenance of Constant Environment Regulation of ICP Control of Respiration Clearance of Waste Products Provides buoyancy and cushioningReduces the effective weight of the brainProtects against deformation caused by acceleration and deceleration...
