Antibiotics must penetrate CSF and be given in an appropriate bactericidal dosage Recommended empirical therapy is based upon age given potential causative organisms Adults <60 years of age Adults ≥60 years of age No Penicillin Allergy Cefotaxime 2 g 6 hourly...
Resuscitation & Supportive Management Ensure appropriate staff available to manage patientABC approach treating abnormalities as found:Consider need for intubation for airway protection:Strongly consider if GCS <12Maintain adequate blood pressure aiming MAP...
CT imaging is important when raised ICP suspected: Lumbar puncture may precipitate cerebral herniation Should be performed if in all patients presenting with: Focal neurologic deficits (excluding cranial nerve palsies) New-onset seizures Severely altered mental status...
Opening Pressure Appearance Cell Differential WCC (per mm3) Protein (g/L) Glucose-Serum Ratio Lactate Gram stain Microscopy & culture PCR Other Normal 5-20 Normal Normal <3 0.2-0.4 0.5-0.66(2.5-3.5 mmol/L) Normal Normal - - - Bacterial Meningitis >30 Turbid...
Opening Pressure Appearance Cell Differential WCC (per mm3) Protein (g/L) Glucose-Serum Ratio Lactate Gram stain Microscopy & culture PCR Other Normal 5-20 Normal Normal <3 0.2-0.4 0.5-0.66(2.5-3.5 mmol/L) Normal Normal - - - Viral Meningitis Normal or slightly...