What are the effects of thyroid hormones (T3 & T4)? Effects on Metabolism Increase basal metabolic rate of most tissues (Long duration of action):Increased heat productionIncreases cardiac metabolic rate:Ionotropic / chronotropic effectIncreased lipolysis &...
What are the essential features of thionamides? Clinical EssentialsPharmacodynamics Examples Thiouracils: Propylthiouracil Imidazoles: Methimazole Carbimazole Indications Thyroid storm After radioactive iodine treatment Before radioactive iodine treatment or...
Which drugs have an anti-thyroid effect and what are their mechanisms? Inhibition of Ionic Trapping Inhibition of Hormone Synthesis Inhibition of Hormone Release Prevention of Peripheral Conversion to Thyroid Hormone Destruction of Thyroid Tissue Examples...