- ICP >15 mm Hg is elevated
- Management is mostly extrapolated from TBI where treatment is recommended for ICP >22 mm Hg (Brain Trauma Foundation Guidelines):
- Values above this level are associated with increased mortality
- However, this single threshold is probably an oversimplification:
- Time spent over the value and its intensity is more important (the ‘ICP dose’)
- Prolonged exposure to values below the threshold may still be harmful
- Also influenced by cerebral perfusion pressure (CPP):
- If CPP low (<50mmHg) ICP no longer a predictor
- Moderate elevations in ICP may be better tolerated at higher CPP
