• Aim of drainage is to remove infected material without breaching the peritoneum
  • Optimum method remains controversial – usually dependent upon local resources and expertise:
Percutaneous Drainage
  • Associated with fewer complications than surgical necrosectomy though no mortality benefit
  • Avoids surgical necrosectomy in 30-50% of cases
  • Can be considered as a bridge to surgery in patients to unstable placement of a drainage tube into the fluid collection
Endoscopic Transluminal Drainage
  • Like percutaneous drainage associated with less morbidity and cost than surgical necrosectomy
  • Involves insertion of a stent to drain necrotic cavity into gastric or duodenal lumen
  • Used only in carefully selected patients and is dependent on local expertise.
Surgical Necrosectomy
  • Once the gold standard now less frequently used as first line
  • Debridement is done bluntly with hydrosonic irrigation frequently used to avoid vascular injury
  • May require multiple operations to achieve adequate debridement