Advantages
Disadvantages
High Blood Flows
  • A lower filtration fraction required thus reducing the risk of filter clotting
  • Easier to match ultrafiltration rates and therefore fluid removal targets
  • Increased risk of haemodynamic instability
  • Increased risk of hypothermia or haemolysis
  • Requires well-functioning access to prevent high suction pressures developing
Low Blood Flows
  • Reduced haemodynamic instability
  • Reduced risk of filter related complications
  • Lower suction pressures needed to achieve flow rates
  • Increased risk of filter clotting due to high filtration fractions
  • More challenging to meet fluid removal targets