Skin
Initial Phase:
- Erythematous, dusky red, flat macules
- Lesions symmetrically distributed on face, trunk and limbs
Late Phase:
- Lesion coalesce to form flaccid blisters
- Epidermal detachment
Mucous Membranes
- Eyelid oedema, redness and discharge
- Buccal erosive haemorrhagic lesions, white pseudomembranous crust
- Crust on lips
- Genital erosive haemorrhagic lesions, painful urination
Extracutaneous Sites
- Respiratory Tract: Respiratory distress 1
- GI Tract: Nausea 1, diarrhoea 1, malabsorption 1, colonic perforation 1
- Renal Tract: Proteinuria 1, haematuria 1