• Hypocalcaemia – due to chelation
  • Hypomagnesaemia – Mg2+ is also chelated
  • Hypernatraemia – high sodium load in hyperosmolar trisodium citrate
  • Metabolic alkalosis – citrate is metabolised to bicarbonate
  • Metabolic acidosis (RAGMA) – caused by the citrate accumulation if there is impaired metabolism (e.g. liver failure)