What are the complications of bacterial meningitis that could occur in a patient admitted to the critical care unit with meningitis?

Neurological
  • Focal neurologic deficits (37%)
  • Seizures (17%)
  • Hydrocephalus (5%)
  • Ischaemic stroke (25%)
  • Haemorrhagic stroke (3%)
  • Subdural empyema (2%)
  • Sinus thrombosis (1%)
  • Deafness (20%)
  • Cerebral venous sinus thrombosis
  • Intellectual deficit
Systemic
  • Death (15-20%)
  • Cardiorespiratory failure (30%)
  • Severe sepsis
  • Peripheral ischaemia and gangrene
  • Syndrome of Inappropriate ADH secretion
  • Waterhouse-Friderichsen syndrome (Adrenal gland failure)