What are the complications associated with acute severe pancreatitis?

Local (Pancreatic)
  • Interstitial Oedematous pancreatitis:
    • Peripancreatic collection
    • Pseudocyst (pancreatic fluid surrounded by a wall of fibrous or granulation tissue)
    • Abscess (circumscribed collection of pus)
  • Necrotising pancreatitis:
    • Sterile parenchymal necrosis
    • Infected parenchymal necrosis
  • Pancreatic insufficiency (and Type 3c Diabetes)
Regional
  • Ascites
  • Portal vein / splenic thrombosis
  • Intraperitoneal bleeding
  • Retroperitoneal bleeding
  • Bowel obstruction
  • Enteric fistulas
  • Intrabdominal hypertension
Systemic
  • Sepsis
  • Multiorgan failure
  • Respiratory:
    • Respiratory failure
    • ARDS
    • Effusions
  • DIC
  • Renal failure
  • GI Bleeding