Primary
- Congenital (5%) - typically present in late infancy or childhood
- Acquired idiopathic (autoimmune)
Secondary
(To a known Trigger)
- Infection:
- HIV
- CMV
- HBV / HCV
- Pregnancy
- Bone marrow transplant
- Drugs:
- COCP and hormonal treatments
- Quinine
- Interferon and immunosuppressants
- Simvastatin
- Antiplatelets
- Malignancy
- Acute pancreatitis