Treatment of Eye Involvement
  • Early ophthalmology review and review daily thereafter during acute illness
  • Frequent application of lubrication (hyaluronate or carmellose eye drops 2 hourly)
  • Corticosteroid drops (dexamethasone 0.1% twice a day) may reduce damage
  • If evidence of ulceration topical antibiotic prophylaxis should be used (e.g. moxifloxacin drops four times a day)
Treatment of Mouth Involvement
  • Manage lips with soft white soft paraffin ointment every 2 hours
  • Clean the mouth daily with an oral sponge
  • Use regular mouthwashes:
    • Anti-inflammatory: rinse or spray containing benzydamine hydrochloride every three hours
    • Anti-septic: rinse containing chlorhexidine twice a day
    • Corticosteroid: mouthwash (e.g. betamethasone sodium phosphate) four times a day
Treatment of Urogenital Involvement
  • Daily review is required during the acute illness
  • Corticosteroid cream should be administered to involved but non-eroded surfaces
  • Gynaecology review recommended for females to consider need for vaginal dilators
Treatment of Airway Involvement
  • Mechanical ventilation may be required if pulmonary infiltrates and respiratory failure develops
  • Fibreoptic bronchoscopy is useful to washout of necrotic bronchial epithelium