Key Principles
- Secure the airway if obtunded
- Instigate neuroprotective measures
- Manage hypertension to prevent rebleeding whilst maintaining CPP
- Secure the aneurysm early
- Monitor for and manage complications
Resuscitation & Supportive Care
- Consider need for intubation:
- Intubation if not maintaining airway
- May require semi-elective intubation if not protecting adequately or for neuroprotective measures
- Tape tube in position
- Manage hypertension / hypotension
- Until aneurysm secured target systolic blood pressure <180mmHg-160mmHg (ESO/AHA)
- If required use a titratable IV antihypertensive and invasive arterial monitoring
- Maintain MAP >90mmHg (ESO)
- Manage arrhythmias
- Manage seizures with benzodiazepines, phenytoin and levetiracetam
- Instigate appropriate neuroprotective measures:
- Maintain CO2 4.5-6.0 kPa, pO2 >10
- Sit up, avoid neck lines
- Analgesics, laxatives, antiemetics to reduce ICP
- Maintain glucose 6-10mmol and temperature <37.5
- Careful management of fluids:
- Urinary catheter and fluid balance monitoring for all patients
- Aim for euvolaemia
- Reverse any coagulopathy
- DVT prophylaxis:
- Mechanical methods until aneurysm secured
- LMWH >12 after surgical clipping
Specific Management
Secure the aneurysm:
- Should be secured within 72 hours
- Multi-disciplinary decision based on patient and aneurysm characteristics
- Coiling: first line as better functional outcomes at one year
- Clipping: for those not amenable to coiling (anatomically and location)
- Consider tranexamic acid if likely to be a delay in securing aneurysm
Manage complications:
- Prevention and management of vasospasm:
- Physical: Targeted hypertensive therapy, maintain euvolaemia
- Pharmacological: nimodipine prevent hypomagnesemia:
- Start immediate nimodipine 60mg 4 hourly NG/PO
- Interventional: Intra-arterial stenting, intra-arterial nimodipine
- Treat hydrocephalus
- Emergency EVD placement if obtunded
- Consider osmotic therapy as temporising measure
Referral & Deposition
- Needs urgent discussion with neurosurgical teamBest managed at high volume centres with neurosurgical and IR services
- Operating theatre if urgent EVD placement required
- ICU if intubated or Neuro HDU prior to securing aneurysm
- Consider need for cerebral oxygen / pressure monitoring