SOE 718: Head Injury & Sedation

SOE Format: Please answer the following questions on the given topic The case will be displayed with each question followed by an answer, allowing you to review your given response A timer is available for use to determine the given time period A 28-year-old man was...

Case Information

The nurse asks you to assess the patient because there is a worsening lactic acidosis with a lactate of 7.4 mmol/L and a base excess of -14...

What are the causes of a lactic acidosis?

Causes of Lactic acidosis are classically divided into 2 types by the Cohen & Woods classification based upon the presence or absence of an oxygen demand/delivery mismatch: Type A: Oxygen Demand / Delivery Mismatch(Anaerobic respiration as a result of tissue...

Case Information

The consultant has reviewed the patient and is concerned about propofol related infusion syndrome (PRIS) given the high levels of sedation he has been...

What is propofol related infusion syndrome (PRIS)?

Recently defined as: Occurring in critically ill patients receiving propofol infusions, typically either high dose (>5 mg / kg / h ) or of long duration (>48 h), and is characterised by one or more of otherwise unexplained metabolic acidosis, rhabdomyolysis, or...