Can be considered in 4 steps: 1. Iodide Trapping 2. Iodide Oxidation & Organification 3. Storage in Colloid with Thyroglobulin 4. Secretion of Thyroid Hormones Iodine obtained in diet from dairy, grains and meat (150mg/day required)Reduced to the inorganic form...
<1% transported freely in plasma unbound to plasma proteins: Forms the active portion of the hormone Mostly transported by non-covalent binding to plasma proteins: Thyroid binding globulin (TBG) – predominant transport protein Transthyretin Albumin TBG has...
Thyroid hormone production is regulated by a series of negative feedback loops Thyroid stimulating hormone (TSH) is an important regulator: Peptide hormone produced in the anterior pituitary gland Stimulates the production and release of thyroid hormones TSH...
An arrangement by which blood passes from one set of capillaries, through a large vessel or vessels, to another set of capillaries before returning to the systemic...
