What is the difference between MOA-A and MOA-B?

Separate genes encode two isoforms of MAO (types A and B), which were distinguished by their specificity to particular catecholamines: MAO-A MAO-B Involved in the metabolism of serotonin, noradrenaline, adrenaline and tyramineHigh concentrations in brain, gut, liver,...

How can you classify monoamine oxidase inhibitors (MAOIs) ?

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What is the Tyramine (“cheese”) reaction?

Tyramine is a vasoactive amine which promotes hypertension: Causes the release of noradrenaline leading to elevated blood pressure Tyramine is usually metabolised by monoamine oxidase (MOA-A) In presence of monoamine oxidase inhibition, tyramine can accumulate...