SOE 389: PONV

Introduction You are assessing a 36-year-old lady preoperatively who is due to undergo a laparoscopic ovarian cystectomy. She has had one previous anaesthetic and developed severe postoperative nausea and vomiting (PONV). She is otherwise fit and well. She does not...

What are the risk factors for developing PONV?

Patient Factors Anaesthetic Factors Surgical Factors Female gender (x3 risk - biggest risk factor)Younger ageNon-smokerHistory of PONV previouslyHistory of Motion sicknessPreoperative anxietyDisease states:UraemiaIntestinal obstructionHypoglycaemiaHypoxia Use of...

Which drugs are most effective in preventing PONV?

Drug Fosaprepitant Casopitant Aprepitant Ramosetron Granisetron Dexamethasone Tropisetron Ondansetron Dolasetron Droperidol Scopolamine Haloperidol Metoclopramide Cyclizine Risk Ratio for PONV 0.06 0.16 0.26 0.44 0.45 0.51 0.52 0.55 0.56 0.61 0.61 0.61 0.73 0.83 Risk...