What is an agonist?

Type (Full) Agonist Description Has affinity for receptorsAble to produce a maximal response Efficacy Efficacy =...

Can you draw the log dose-response curve of a full agonist?

Description The graph is a log dose-response curve with log drug dose on the x-axis and % of maximal effect on the y-axisThe curve sigmoid in shapeThe height of the curve is the maximal effect which for a full agonist is 100%The curve always passes through the ED50For...

What is the ED50 and what does it represent?

Quantal ResponseED50(Median Effective Dose) The dose of a drug that induces a specific response in exactly 50% of the population who take itUsed to define the potency of a...

What is a partial agonist?

Type Partial Agonist Description Has affinity for receptorsProduces a sub-maximal response Efficacy 0 < Efficacy <...