Anticoagulation should be used in all patients requiring RRT for AKI unless: There is an ↑ risk of bleeding They are already receiving systemic anticoagulation KDIGO...
If No Increased Risk of Bleeding Regional citrate rather than heparin as first line unless contraindicatedIf citrate contraindicated or as a second line alternative either unfractionated or low molecular weight heparin If Increased Risk of Bleeding Regional citrate...
All heparins should be stopped but anticoagulation should be continued during RRT as they are pro-thrombotic The direct thrombin inhibitor argobatran is recommended as first-line Other options include Factor Xa inhibitors such as danaparoid or fondaparinux KDIGO...
