IntroductionYou are covering the ICU overnight. The nurse in charge asks you to review a patient who is receiving RRT for AKI secondary to rhabdomyolysis following a major RTC. The filter has clotted for the 3rd time in 24...
All modes of RRT (with the exception of PD) utilise an extracorporeal circuit Contact of blood with the foreign surface results in: Activation of both the intrinsic and the extrinsic pathway of coagulation Activation of platelets Exacerbated by pro-coagulopathic...
The average circuit lifespan varies according to patient groups and anticoagulation used In observational studies mean lifespans of 38 – 124 hours have been...
The goal of anticoagulation with RRT is to: Prevent clotting of the filter Prevent reduced membrane permeability This ensures adequate RRT can be achieved and prevents blood loss in the clotted filter Any benefits must be weighed against: Risk of bleeding Economic...
