SOE 018: ARDS 1

Introduction A 58-year-old lady was involved in a high-speed RTC. Her initial injuries included liver lacerations which were managed conservatively and multiple ling bone fractures which have been reduced and immobilised. You are called to see her on the ward several...

What is the criteria for the diagnosis of ARDS?

ARDS is diagnosed clinically using the international consensus criteria (The Berlin Criteria) Essential components required for diagnosis are: PaO2/FiO2 ratio of ≤39.9 kPa / ≤300 mmHg Acute onset (within 1 week of known clinical insult) Bilateral opacities on CXR (not...

How can the severity of ARDS be classified?

The Berlin Criteria classifies ARDS severity based upon the P/F ratio when on a PEEP of 5  Mild Moderate Severe P/F Ratio (mmHg / kPa) 201 - 300 mmHg (≤ 39.9 kPa) 101 - 200 mmHg (≤ 26.6 kPa) ≤ 100 mmHg (≤ 13.3 kPa) Related...

Can you outline the pathophysiology of ARDS?

Stage 1Exudative0-7 days 2Proliferative7-14 days 3Fibrotic>14 days Histopathology Acute inflammatory reaction in the lung caused by insult to the epitheliumAlveoli fill with neutrophils, blood and a protein-rich pulmonary oedemaAssociated alveolar epithelial and...

How would you work-up the patient with suspected ARDS?

To Determine Diagnosis Clinical Diagnosis (Berlin Criteria) - all 4 of:PaO2/FiO2 ratio ≤300Acute onset (within 1 week of known clinical insult)Bilateral opacities on CXR (not explained by effusions, collapse, or nodules)Respiratory failure not fully explained by...