Features
Implications
- Liver function is initially immature, with decreased hepatic enzyme function
- Drug metabolism may be slower leading to a longer duration of action (e.g. barbiturates and opioids)
- Liver and spleen ride comparatively low within the abdomen and have minimal protection from ribs
- Intestines, especially the sigmoid and right colon, are not fully attached in the peritoneal cavity
- Abdominal viscera more prone to injury, particularly in blunt trauma