Group
Drug
Dose
Timing
Adverse Effect
Serotonin (5-HT3 receptor) anatagonists
Ondansetron
4-8mg IV
End of surgery
Headaches, constipation, raised liver enzymes
Serotonin (5-HT3 receptor) anatagonists
Granisetron
1mg IV
End of surgery
Headaches, constipation, raised liver enzymes
Serotonin (5-HT3 receptor) anatagonists
Tropistron
2mg IV
End of surgery
Headaches, constipation, raised liver enzymes
Corticosteroids
Dexamethasone
4-10mg IV
After Induction of Anaesthesia
Increased blood glucose level, hyper/hypotension
Neurokinin (NK-1 receptor) antagonists
Aprepitant
40-80mg PO
Before Induction of Anaesthesia
Headaches, constipation, fatigue
Neurokinin (NK-1 receptor) antagonists
Fosaprepitant
150mg IV
Before Induction of Anaesthesia
Headaches, constipation, fatigue
Neurokinin (NK-1 receptor) antagonists
Casopitant
150mg PO
Before Induction of Anaesthesia
Headaches, constipation, fatigue
Anticholinergics
Scopolamine (Hyoscine)
Transdermal patch
Before Induction of Anaesthesia
Dizziness, dry mouth, visual disturbance
Dopamine Antagonists & Butyrophenones
Metoclopramide
10-25mg IV
After Induction of Anaesthesia
Sedation, hypotension (fast injection)
Dopamine Antagonists & Butyrophenones
Droperidol
0.625-1/25mg IV
After Induction of Anaesthesia
Sedation, hypotension (fast injection)
Dopamine Antagonists & Butyrophenones
Haloperidol
1-2mg IV
After Induction of Anaesthesia
Sedation, hypotension (fast injection)
Anthistamine
Dimenhydrinate
25-50mg IV
After Induction of Anaesthesia