- Sudden death:
- Asymptomatic disease: 1%
- Symptomatic disease: 50%
- Left ventricular failure
- Arrhythmias:
- Ventricular arrhythmias (more common)
- Supraventricular arrhythmias
- Heart block
- Infective endocarditis
- Embolic phenomena (disintegration of the aortic valve or concomitant aortic atheroma)
- Haemolytic anaemia
- Von Willebrand factor deficiency and lower gastrointestinal tract bleeding due to angiodysplasia