- Thyroid hormone production is regulated by a series of negative feedback loops
- Thyroid stimulating hormone (TSH) is an important regulator:
- Peptide hormone produced in the anterior pituitary gland
- Stimulates the production and release of thyroid hormones
- TSH production is stimulated by:
- TRH production
- Low serum levels of thyroid hormones
- TSH production is inhibited by:
- High serum levels of thyroid hormones (negative feedback loop)
- High serum levels of TSH (ultra-short negative feedback loop)
- Thyrotropin-releasing hormone (TRH) is another important regulator:
- Peptide hormone produce in the hypothalamus
- Stimulates the production and release of TSH
- TRH production is stimulated by:
- Low serum levels of thyroid hormones
- TRH production is inhibited by:
- High serum levels of thyroid hormones (negative feedback loop)
