- Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy resulting in a consumptive thrombocytopenia, haemolytic anaemia and ischaemic end-organ damage
- It occurs due to a deficiency in the activity of a specific von Willebrand factor cleaving protein (vWF-CF) known as ADAMTS13
- It is an intensive care and haematological emergency
