Type
Type
Recommendation
Primary
Congenital
  • Bicuspid valve (2% prevalence - typically presents 4th to 6th decade)
  • Congenital subaortic membrane
  • Other congenital heart disease (e.g. supravalvular stenosis)
Primary
Acquired
  • Degenerative (senile) calcification - most common in the UK
  • Rheumatic heart disease (usually associated with mitral valve disease)
  • Systemic Lupus Erythematosus (SLE)
  • Paget's disease
  • Radiation
  • Drugs