Chemical PropertiesWeak organic acidpKa of 11The pH of the presenting solution is 6-8.5:At this pH, and at physiological pH (7.4), it is almost entirely (>99%) unionisedTherefore has minimal water...
Presented in a lipid water emulsion due to lipid-soluble nature Emulsion contains (%by weight)Propofol (1% or 2%)Soya-bean oil (10%) - acts as lipid solvent for propofolPurified egg lecithin, a type of phosphatide (1.2%) - emulsifying agent that stabilise the oil...
Indications & Dosing Should be dosed based upon ideal body weight (IBW) Induction of Anaesthesia Maintenance of Anaesthesia Procedural sedation Sedation of ventilated patients on ICU Anti-emesis (in low doses) Management of Status Epilepticus Induction dose...
